Treatment outcomes of primary radiotherapy / chemoradiotherapy for locally advanced bladder cancer
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Original Article
P: 87-93
2020

Treatment outcomes of primary radiotherapy / chemoradiotherapy for locally advanced bladder cancer

Acta Haematol Oncol Turc 2020;53(1):87-93
1. Department of Radiation Oncology, Ankara Yıldırım Beyazıt University, Ankara, Turkey
2. Department of Radiation Oncology, Elazığ Fethi Sekin City Hospital, Elazığ, Turkey
3.
No information available.
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Received Date: 2019-04-08T21:02:11
Accepted Date: 2020-04-28T11:17:44
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Abstract

INTRODUCTION

The aim of this study was to evaluate the acute toxicity and survival outcomes of patients with bladder carcinoma who underwent primary radiotherapy - chemoradiotherapy.

METHODS

The treatment results and acute toxicity of 39 patients with local advanced bladder cancer treated with RT-CRT were evaluated in the Radiation Oncology Clinic of Ankara Atatürk Training and Research Hospital between 2009-2017.

RESULTS

Overall survival was 32% and disease-free survival was 28% at median 23-month follow-up. Grade 3 toxicity was observed in 3 patients, one of them was genitourinary toxicity and 2 was gastrointestinal toxicity. All patients completed the planned treatment scheme.

DISCUSSION AND CONCLUSION

In this disadvantaged group, which did not undergo surgical treatment for various reasons, CRT results could not reach the results obtained by surgery; however, randomized controlled trials are needed for the optimal treatment scheme in this patient group.