Abstract

The evolvings of alternative treatment choices as cytoreductive surgery combined with hyperthermic chemotherapy for peritoneal surface malignancies creates new responsibilities for anesthesiologists to manage the procedure with sufficient information. To adequately care for these patients, anesthesiologists should control complex malfunctions of physiologic mechanisms, such as hypo-hyperthermia, blood loss, electrolyte abnormalities, coagulopathies, increased cardiac index, oxygen consumption, decreased systemic vascular resistance and toxic effects of chemotherapy agents related with both longer duration of radical surgery and the effects of hyperthermic chemotheraphy.