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E-ISSN: 3061-9947
The long-term oncological results of patients under 55-year-old who underwent radical retropubic prostatectomy for localized prostate cancer
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Original Article
VOLUME: 53 ISSUE: 2
P: 219-224
2020

The long-term oncological results of patients under 55-year-old who underwent radical retropubic prostatectomy for localized prostate cancer

Acta Haematol Oncol Turc 2020;53(2):219-224
DOI: 10.5505/aot.2020.30316
Süleyman Bulut 1
Samet Şenel 1
Yalçın Kızılkan 1
Cüneyt Özden 1
Binhan Kağan Aktaş 1
1. Sağlık Bilimleri University, Ankara Numune Training and Research Hospital, Department of Urology, Ankara
2.
No information available.
No information available
Received Date: 2020-01-11T18:00:38
Accepted Date: 2020-09-04T10:05:20
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Abstract

INTRODUCTION

Prostate cancer (PK) is the most common type of cancer in men and is seen especially in older ages. In this study we presented the long-term oncological results of patients who are under 55-year-old underwent radical retropubic prostatectomy (RRP).

METHODS

In this study we diagnosed with PK in 346 patients between January 2000 and June 2017 and underwent RRP in our clinic and their datas were analyzed retrospectively. Patients were divided into two groups (under (n: 64 (%18.5)) and over (n: 282 (%81.5)) 55-year-old). The results of gleason score (GS), positive surgical margin (PSM), seminal vesicle invasion (SVI), lymph node invasion (LNI, extracapsular invasion (ECI) were evaluated.

RESULTS

In our study, the mean follow-up was 80.1 ±36.1months and BCR was detected in %22.3 (n: 77) of patients during follow-up. In multivariate logistic regression analysis, BCR-related factors were; serum PSA level was>20 ng/ml, ECI, SVI, PSM and GS in RRP spesimens (p<0.05). There was no statistically significnt difference in BCR-free survival rates between age groups (under 55-year-old and older) (p: 0.9).

DISCUSSION AND CONCLUSION

In our studyi statistically significant relationship was found between BCR and presence of high PSA level, ECI, SVI, PSM and GS in parallel with the litarature; however there was no statistically significant between agre groups and BCR.