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The Etiology of Acute Kidney Injury in Patient with Solid Tumor
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Original Article
VOLUME: 53 ISSUE: 3
P: 410-414
2020

The Etiology of Acute Kidney Injury in Patient with Solid Tumor

Acta Haematol Oncol Turc 2020;53(3):410-414
DOI: 10.5505/aot.2020.42275
İbrahim Yıldırım 1
Esra Durmuşoğlu 1
1. Sağlık Bilimleri Üniversitesi Medicine School, Dr. Abdurrahman Yurtaslan Ankara Oncology Education and Research Hospital
2.
No information available.
No information available
Received Date: 2020-05-31T15:34:27
Accepted Date: 2020-12-30T17:35:34
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Abstract

INTRODUCTION

The aim of this study is to evaluate the etiology of renal failure in patients with solid tumor.

METHODS

The study was included 100 patients with acute renal failure. These patients were selected among hospitalized patients with solid tumor in Dr. Abdurrahman Yurtaslan Ankara Oncology Education and Research Hospital. The data of these patients were analyzed retrospectively. The presence of acute kidney injury was determined according to RIFLE-AKIN criteria. The patients were retrospectively classified into the following 3 groups: Prerenal, renal and postrenal acute kidney injury (AKI) groups. In these groups, specific causes of renal failure and comorbidities such as diabetes, coronary arteria disease etc. were compared using the chi square statistical analyze.

RESULTS

The most common type of renal failure in patients with solid tumor was prerenal acute kidney injury (%55). The most common specific cause in all groups with prerenal AKI was inadequate oral intake and gastrointestinal loss. No significant difference was detected in terms of the average age (p=0.256) and in terms of frequency of sex, diabetes mellitus, hypertension, smoking, whether chemotherapeutic agents in three groups (p=0.259, p=0.739, p=0.789, p=0.945, p=0.339). There was a marked increase in the frequency of ischemic acute tubular necrosis in the study population.

DISCUSSION AND CONCLUSION

The causes of acute renal failure may differ from actuarial estimates in patients with cancer. Complete documentation of these causes in this population with tumor may increase surveys of these patients. In developing countries, multicenter prospective trials are needed to evaluate the etiology of all renal failure in this population.