Abstract

INTRODUCTION

Modelling of heterogeneous survival data of breast cancer patients and the determination of the factors affecting the time of survival.

METHODS

Retrospectively obtained survival data of 181 breast cancer patients were analyzed by means of the model of frailty models.

RESULTS

The median of survival time of 181 breast cancer patients analyzed was determined as 74 months (95 % CI, 61.88 to 86.78). Size of the tumor, number of Iymph nodes and the negativity of hormone receptor (p<0.05) were found as important factors influencing the failure. In addition, the time between the chemotherapy and surgical operations influence the failure directly (p=0.002). It is found that a breast cancer patient is under 3 times more risk than any other patients (p<0.001).

DISCUSSION AND CONCLUSION

The analysis findings have put forward that there may also be some latent genetic or environmental factors influencing the survival time of the breast cancer patients in addition to factors such as the size of the tumor, size of the lymph node, the negativity of hormone receptor and the time between the chemotherapy and surgical operations and these latent factors may increase the risk level three fold.