Abstract

INTRODUCTION

Inverted papilloma (IP) is the most common epithelial tumor of the sinonasal region. It is crucial for predisposition to the recurrence and malignancy. The incidence of squamous cell carcinoma (SCC) foci is between 5% and 15%. It is usually seen in 5-6th decade and 2 times more frequent in males. It commonly originates from the lateral nasal wall, and secondly from the maxillary sinus. The most common finding is the unilateral nasal obstruction. The treatment is total/wide surgical resection.

METHODS

The patients who underwent surgery with the diagnosis of sinonasal IP between 2007-2017 in a tertiary referral center were included in the study. The patients were evaluated in terms of demographic features, signs and symptoms (clinical and radiological), surgical, pathological features, postoperative complications, and long-term follow-up results.

RESULTS

Twelve of the patients were male (86%), the median age was 56 years (range: 36-79 years). Pathological examination was generally HPV (-), and 4 patients with sinonasal IP (%29) had SCC, in-situ SCC focus, or SCC transformation in the follow-up period.

DISCUSSION AND CONCLUSION

Although inverted papilloma is a benign neoplasm, it is an important disease for malignant content and/or transformation. Consequently, the close follow-up is required for these patients.