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Serum Level Of The Soluble CD 40 Lıgand And Mean Corpuscular Volume, Mean Platellet Volume In Patıents Wıth Ischemıc And Hemorrhagıc Cerebrovascular Dısease
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Original Article
VOLUME: 53 ISSUE: 2
P: 349-356
2020

Serum Level Of The Soluble CD 40 Lıgand And Mean Corpuscular Volume, Mean Platellet Volume In Patıents Wıth Ischemıc And Hemorrhagıc Cerebrovascular Dısease

Acta Haematol Oncol Turc 2020;53(2):349-356
DOI: 10.5505/aot.2020.94824
Ömer Canpolat 1
Metin Ateşçelik 2
Nevin İlhan 3
İbrahim Yıldırım 4
Mustafa Yılmaz 2
Mehmet Çağrı Göktekin 2
1. Department of Emergency, Elazig Fethi Sekin City Hospital, Elazig, Turkey,
2. Department Of Emergency, Firat University Hospital, Elazig, Turkey,
3. Department Of Biochemistry, Firat University Hospital, Elazig, Turkey,
4. Dr. Abdurrahman Yurtaslan Ankara Oncology Training And Research Hospital, Ankara, Turkey.
5.
No information available.
No information available
Received Date: 2020-03-09T20:06:45
Accepted Date: 2020-09-04T11:31:32
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Abstract

INTRODUCTION

The clinical importance of biochemical indicators as well as imaging methods in diagnosis and prognosis of cerebrovascular disorder increase continuously. The aim of the present study is to determine the relationship among soluble-CD40 ligand, mean platelet volume (MPV), mean red blood cell volume (MCV) levels and early prognosis in ischemic and hemorrhagic stroke.

METHODS

100 ischemic and 80 hemorrhagic stroke patients and 50 healthy volunteers were included in the study. Demographic data, Glasgow Coma Scale, intraserebral hemorrhage scale and NIH Stroke Scale/Score results for stroke, hemoglobin, MPV, MCV and sCD40L measurement results were enrolled.

RESULTS

MPV levels for patients with ischemic and hemorrhagic stroke were significantly higher than the control group. There was no a significant correlation between blood MCV/serum sCD40L levels and strokes. sCD40L levels for exitus patients was statistically significantly lower when compared to sCD40L levels in living patients.

DISCUSSION AND CONCLUSION

MPV levels in patients with stroke increase considerably. The low level of sCD40L may be a parameter associated with early unfavorable prognosis and mortality.