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Radical nephrectomy for large renal tumors: evaluate perioperative and oncological outcomes of stage T2a and T2b
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Original Article
VOLUME: 50 ISSUE: 2
P: 94-98
2017

Radical nephrectomy for large renal tumors: evaluate perioperative and oncological outcomes of stage T2a and T2b

Acta Haematol Oncol Turc 2017;50(2):94-98
DOI: 10.5505/aot.2017.21932
Taha Numan Yıkılmaz
Erdem Öztürk
Halil Başar
1. Department of Urology, Ankara Dr. Abdurrahman Yurtaslan Oncology Training and Research Hospital, Ankara, Turkey
2.
No information available.
No information available
Received Date: 2017-04-11T13:05:59
Accepted Date: 2017-08-28T11:55:57
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Abstract

INTRODUCTION

We aimed analyzing the perioperative and oncological outcomes of >7 cm renal tumors treated with open radical nephrectomy.

METHODS

We retrospectively reviewed records of 36 cases undergoing open radical nephrectomy due to T2 clinical stage (>7 cm) between June 2010 and October 2015. Five cases were excluded which have pathology with oncocytoma, angiomyolipoma and ksanthagranulamatousis pyelonephritis. The cases were divided into 2 groups: T2a (7-10 cm) and T2b (<10 cm). The cases demographics, tumor characteristics, perioperative and oncological outcomes were compared.

RESULTS

Of the 31 cases, 23 (71%) had tumors stage T2a and 8 (29%) had tumors clinical stage T2b. The tumor stage was more often upstaged 8 cases (34%) in 23 patients at <10 cm, 4 cases (50%) in 8 patients at >10 cm. The clinical stage correlated with the pathologic size in 61% of the patients. A total of 9 cases (29%) developed recurrence, including 5 (16%) with local and 4 (13%) with distant recurrence. The sites of distant recurrence included lung in 2, brain in1 and bone in 1 case.

DISCUSSION AND CONCLUSION

The significant predictors of recurrence were papillar histological variant, high Fuhrman grade, renal vein invasion and perinephric extension. Stage T2b increased recurrence risk but not alone.