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Frequency of ASFA 3 Category Therapeutic Plasmapheresis in Reanimation Intensive Care Units
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Original Article
VOLUME: 52 ISSUE: 3
P: 463-469
2019

Frequency of ASFA 3 Category Therapeutic Plasmapheresis in Reanimation Intensive Care Units

Acta Haematol Oncol Turc 2019;52(3):463-469
DOI: 10.5505/aot.2019.54771
Aysun Şentürk Yıkılmaz 1
Firdevs Tuba Bozkurt 2
Sema Akincı 3
İmdat Dilek 1
1. Yildirim Beyazit University, Hematology Department, Ankara, Turkey
2. Yildirim Beyazit University, Anesthesiology and Intensive Care Medicine Department, Ankara, Turkey
3. Ataturk Training and Research Hospital, Hematology Department, Ankara, Turkey
4.
No information available.
No information available
Received Date: 2019-09-03T18:08:20
Accepted Date: 2019-12-27T14:31:03
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Abstract

INTRODUCTION

Therapeutic plasma exchange (TPD) is a procedure in which the majority of patient plasma is replaced with replacement fluids and returned to the patient. TPD procedure is used as a primary treatment or complementary method in many diseases including hematologic, rheumatologic, neurological and toxicological diseases. Nowadays, the frequency of TPD usage in intensive care units has increased. We aimed to present the clinical features of patients undergoing TPD in the reanimation intensive care unit between 2010-2017.

METHODS

The data of the Apheresis Unit of Atatürk Training and Research Hospital were analyzed retrospectively. Fresenius COM.TEC device was used for apheresis operations in our center. Age, sex, indication for TPD, number of TPD, and American Apheresis Association (ASFA) therapeutic apheresis category of 41 patients who were followed in reanimation intensive care unit were retrospectively analyzed. 171 TPD operation evaluated.

RESULTS

The median age of the patients was 54 (19-88) years. The ratio of female to male was 19/22 (46.3% / 53.7%). According to ASFA categories, 8 cases were category 1, 5 cases were category 2, 28 cases (68.4%) were category 3. According to the reasons; TPD was performed in 2 (4.9%) suicid, 7 (17.1%) neurological, 14 (34.1%) acute liver failure-hyperbilluribinemia, 9 (22%) rheumatologic, 2 (4.9%) renal transplant rejection, 2(4.9%) septic shock patients. During the follow-up, it was determined that 23 patients (54.8%) died and 18 patients (42.9%) were alive.

DISCUSSION AND CONCLUSION

In our center, TPD was performed mostly in ASFA category 3 patients. In this group, TPD is supportive of the main treatment and is used specific to the condition of the case. As a result; Individual approach to the indications of TPD in ICU patients is important and multidisciplinary communication between disciplines may increase the applicability of plasmapheresis as a complementary treatment option.