Abstract
INTRODUCTION
Endoscopic retrograde cholangiopancreatography (ERCP) is an important procedure in diagnosis and treatment of pancreaticobiliary diseases. In this study we aimed to evaluate outcomes, procedural interventions, complications and relations between procedural interventions and complications of ERCP procedures.
METHODS
A total of 774 ERCP procedures performed on 574 patients were included and investigated retrospectively in this study.
RESULTS
Endoscopic cannulation was successful in 88.4% of the cases. The most reported outcomes were choledocholithiasis (39.5%), stenosis in the common bile duct (22%) and microlithiasis (20.9%). The incidence of clinically significant procedure related complications was 14.8% in total. Pancreatitis was observed in 9.8% of the cases, clinically significant bleeding was observed in 4% of the cases, and cardiopulmonary complications were observed in 1.9% of the cases. The mortality rate was found to be 0.9%. Pre-cut sphincterotomy technique was found to be more frequently applied in failed cannulation cases (p=0.000). Post-ERCP bleeding and pancreatitis were observed more frequently in cases which pre-cut sphincterotomy technique was applied (p=0.009; p=0.007). Post-ERCP pancreatitis was found to be more frequent in cases which pancreatic stent implantation was performed (p=0.001).
DISCUSSION AND CONCLUSION
It would be appropriate to avoid pre-cut sphincterotomy as much as possible in order to reduce the risk of post-ERCP pancreatitis and bleeding; to postpone the procedure to a latter session in case of failed cannulation instead of traumatizing the papilla further; and prophylactic pancreatic stenting should only be performed in highly experienced centers.