Abstract

INTRODUCTION

Although prostate biopsy is still the gold standard in diagnosis of prostate cancer (PC), multi-parametric MRI (MpMRI) applied with 1.5 Tesla (T) or 3T systems has become an indispensable method in diagnosis. We aimed to compare “Prostate Imaging-Reporting and Data System version2” (PI-RADSv2) scores with pathology of patients who underwent MpMRG (1.5T) for the suspicion of PC.

METHODS

Between January 2017 and January 2020, 52 patients (26 benign, 26 malignant patients) who underwent MpMRI followed by biopsy in our center due to suspicion of PC were included in our study. Age, prostate volume, blood PSA (prostate specific antigen) value, density and pathology of these cases were analyzed. The PI-RADSv2 assessment category was assigned for each patient by an experienced radiologist. The "Chi-square" test and "Student-t" test were used for statistical analysis.

RESULTS

The mean prostate volume of benign group (96.4±77.7) was significantly higher than patients with cancer (47.4±17.3) (p=0.003). Mean PSA value and PSA density in patients with malignancy (PSA value, 13.7±16.5 ng/ml; PSA density, 0.33±0.46 ng/ml/cc) were significantly higher than benign group (PSA value, 6.8±3.3 ng/ml; PSA density, 0.09±0.05 ng/ml/cc, p<0,05). The sensitivity, specificity, negative predictive value and positive predictive value of MpMRI applied with 1.5 T system in detection of significant PC was 73.08% 84.62%, 82.61% and 75.86%, respectively.

DISCUSSION AND CONCLUSION

Considering the high negative predictive value of negative MpMRI findings for significant PC due to PI-RADSv2, MRI can reduce unnecessary biopsy.