Abstract

INTRODUCTION

In this study, we aimed to evaluate the concordance between needle biopsy samples and radical prostatectomy samples in our patients who underwent radical prostatectomy for prostate cancer.

METHODS

In this retrospective study, 167 male patients who underwent radical prostatectomy for prostate cancer between November 2010 and May 2020 were evaluated. Patients whose pathological diagnoses were made by needle biopsy at our center and who did not receive any treatment for prostate cancer before radical prostatectomy were included in the study. 92 patients whose needle biopsies were performed in a different center, 2 patients whose pathological diagnosis was made with transurethral resection material, 1 patient who received hormonotherapy before radical prostatectomy and 1 patient who received radiotherapy were excluded.

RESULTS

The mean age of 71 patients included in the study was 62.3 ± 6.0 (range, 46 - 75) years, and the mean PSA level before diagnosis was 10.0 ± 7.6 (range, 3.2 - 48.1) ng / mL. Suspicious findings were found on digital rectal examination in 31 (43.7%) patients. The concordance between needle biopsy samples and radical prostatectomy samples was 66.2%, 59.2% and 74.6%, respectively, in terms of Gleason score, prognostic group and tumor laterality.

DISCUSSION AND CONCLUSION

Pathological evaluation of needle biopsy samples has a critical role in determining the treatment methods in patients diagnosed with prostate cancer. However, it should be borne in mind that needle biopsy specimens do not predict prostate pathology with high concordance.