Abstract
INTRODUCTION
To evaluate the concordance between the intraoperative frozen section (IFS) and final histopathological results for diagnosing adnexal masses.
METHODS
The data of 274 patients who underwent IFS examination of an adnexal mass were collected retrospectively. The concordance of IFS and final histopathological results for diagnosing adnexal masses was evaluated using the Kappa test, which was calculated by correcting the random fit rate.
RESULTS
The overall agreement rate (94.0%) between the IFS and final pathology results showed strong agreement when evaluated with Cohen’s kappa table (K = 0.847; p < 0.001). The IFS sensitivity values were 99.0%, 68.4%, and 84.0% for benign, borderline, and malignant cases, respectively. Specificity ratios were 84.1%, 99.2%, and 98.7% for benign, borderline, and malignant cases, respectively. Prevalence rates were 74.8%, 6.9%, and 18.3% for benign, borderline, and malignant cases, respectively.
DISCUSSION AND CONCLUSION
Strong concordance between IFS and final pathology results for diagnosing adnexal masses showed that IFS is reliable even for borderline cases, which have the lowest prevalence.