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E-ISSN: 3061-9947
Clinical, radiological and toxicity evaluation of Vestibular Schwannoma patients treated with Cyberknife® stereotactic radiosurgery-radiotherapy
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Original Article
VOLUME: 52 ISSUE: 1
P: 58-63
2019

Clinical, radiological and toxicity evaluation of Vestibular Schwannoma patients treated with Cyberknife® stereotactic radiosurgery-radiotherapy

Acta Haematol Oncol Turc 2019;52(1):58-63
DOI: 10.5505/aot.2019.88700
Gonca Altınışık İnan 1
Süheyla Aytaç Arslan 2
Ebru Karakaya 3
Yıldız Güney 4
1. Ankara Atatürk Training And Research Hospital, Department Of Radiation Oncology
2. Department Of Radiation Oncology Yıldırım Beyazit University, Faculty Of Medicine, Ankara, Turkey
3. Ankara Abdurrahman Yurtaslan Oncology Training And Research Hospital, Department Of Radiation Oncology
4. Memorial Ankara Hospital, Department Of Radiation Oncology
5.
No information available.
No information available
Received Date: 2018-05-28T14:47:51
Accepted Date: 2019-04-09T13:33:53
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Abstract

INTRODUCTION

The current study was done by means of clinical and radiological evaluations of vestibular schwannoma patients who treated with stereotactic radiosurgery or stereotactic radiotherapy using Cyberknife® (Accuray, Sunnywhale, USA).

METHODS

Between June 2009 and September 2014,30 vestibular schwannoma patients were treated in Dr. AY. Ankara Oncology Training and Research Hospital, Department of Radiation Oncology. The patients were assessed before and after radiotherapy retrospectively, for hearing capacity (via Gardner-RobertsonScale), motor function of cranial nerve 7. (via House-Brackmannscale),the sensorial function of cranial nerve 5.

RESULTS

Local control was defined as radiologically stable or regressive disease and achieved for all of the patients at the last control (%100). Preradiotherapy mean values of GRS and HB scores were both statistically different from post radiotherapy mean values (p=0,042 and p=0,046, respectively). Trigeminal toxicity was determined as 7%.

DISCUSSION AND CONCLUSION

When the study results were interpreted, while the local control results were found similar with the literature, trigeminal nerve toxicity values were higher than the reported results. Prospective studies are needed to optimize dose and fraction schedules.