Abstract

Castleman disease (CD) is a lymphoproliferative disorder that is most frequently seen as an asymptomatic mass in the mediastinum. Among the head and neck region, the neck is the most frequent localization. It is seldom localized in the oral cavity. Surgical excision is the primary choice of treatment. The current study presents a patient with previous non-Hodgkin Lymphoma (NHL) history, who was complaining of a mass gradually increasing in size beneath the right and left buccal mucosa and a histopathological diagnosis of Castleman disease – plasma cell type. The related literature is also reviewed.