Abstract

Introduction: Hematopoietic malignancies may also develop in relation to treatment. Here, we report a case of acute lymphoblastic leukemia that developed in a patient who received chemotherapy and radiotherapy due to gastric cancer about 3 years later. Case: A patient with known gastric adenocarcinoma received FUFA (5 Fluoro-uracil / leucoverin) weekly for simultaneous radiotherapy after subtotal gasrectomy. Leukocytosis was detected approximately 3 years later and B cell acute lymphoblastic leukemia (B-ALL) was diagnosed. The Philedelphia chromosome t (9; 22) was positive with RT PCR. The patient was given 12 cycles of POMP maintenance + imatinib 600 mg. The patient who had relapse was started on dasatinib treatment. Discussion: It should be kept in mind that patients with previous chemotherapy may develop ALL instead of MDS and AML.