Presentation of Metastatic Cholangiocellular Cancer with Orbital Metastasis

Cholangiocarcinomas are cancers arising from epithelial cells of the intrahepatic and extrahepatic bile ducts. Most are locally advanced lesions when present. They usually present with jaundice, abdominal pain, and abnormal liver biochemical tests.
Proptosis developed in the right eye of a 49-year-old female patient who was diagnosed with carcinoma metastasis in the right femur and we examined for the primary one. Lacrimal gland biopsy of the patient was found to be compatible with cholangiocarcinoma metastasis. Neuroopthalmologic complications in cholangiocarcinoma are very rare and 10 cases have been reported in the literature.

Metastatik Kolanjýoselüler Kanserin Orbital Metastaz ile Prezentasyonu

Kolanjiokarsinomlar intrahepatik ve ekstrahepatik safra kanallarýnýn epitel hücrelerinden kaynaklanan kanserlerdir. Çoðu prezente olduðunda lokal olarak ilerlemiþ lezyonlardýr. Genellikle sarýlýk, abdominal aðrý ve anormal karaciðer biyokimyasal testleri ile prezente olurlar.
Sað femurda karsinom metastazý saptanýp prýmerýne yonelýk tetkýk ettiðimiz 49 yasýndaký kadýn hastanýn sað gözünde proptozis geliþti. Hastanýn lakrimal bez biyopsisi kolanjýiokarsinom metastazý ile uyumlu saptandý. Kolanjiokarsinomda nörooptalmolojýk komplikasyonlar oldukça nadir olup literatürde 10 vaka bildirimiþtir.