Supra- and Infratentorial Cystic Metastases of Breast Cancer: Case Report

Breast cancer is most frequently metastasize dura, bone and parenchyma in cranial tissue. Symptoms vary according to the location of the metastasis. Masses may be solid, cystic and partial cystic form. Cystic intracranial metastases of breast cancer is very rare. Radiotherapy and/or chemotherapy could be performed after surgery. Forty-eight-year-old female patient was admitted with complaints of headache and generalized tonic-clonic seizure. Patient underwent surgery for cancer of the left breast for eight years ago. Left total mastectomy and left axillary lymphadenectomy was performed. Pathology was determined as adenoid cystic carcinoma. Adjuvant chemotherapy was applied to patients with lymph nodes metastasis detected. Cranial MRI (Magnetic Resonance Imagination) was performed after eight years after breast surgery. In the left frontal and cerebellar midline, large cystic mass lesions were detected in cranial MRI. PET–CT (Positron Emission Tomography) examination was not detected in any other organ metastases. There was no pathology in terms of breast surgery consultation. Both cranial lesions were underwent surgery twice in one week. In the pathological examination of the patient, cystic breast cancer metastasis was detected. Whole brain radiotherapy was performed to the patient after surgery. We want to emphasize that in cranial cystic metastasis, rarely come across if breast cancer metastasis should be considered in differential diagnosis.

Meme Kanserinin Supra- ve Ýnfratentorial Kistik Metastazlarý: Olgu Sunumu

Meme kanserinin kranial metastazlarý; kemik, dura veya beyin parankimine olmaktadýr. Semptomlar metastazýn lokalizasyonuna göre deðiþir. Kitleler; solid, kistik veya parsiyel kistik þekilde olabilirler. Meme kanserinin kistik intrakranial metastazlarý oldukça nadirdir. Cerrahi sonrasý radyoterapi ve/veya kemoterapi uygulanýr. Kýrksekiz yaþýnda bayan olgu, baþ aðrýsý ve generalize tonik-klonik nöbet þikayetleri ile baþvurdu. Sekiz yýl önce sol meme kanseri nedeniyle sol total mastektomi ve sol koltukaltý lenfadenektomi ameliyatý yapýlmýþ. Patolojisi adenoid kistik karsinom olarak gelmiþ. Lenf nodlarýnda metastaz tespit edilen olguya adjuvan kemoterapi uygulanmýþ. Meme ameliyatýndan sekiz yýl sonra yapýlan kranial MRG’sinde (Manyetik Rezonans Görüntüleme) sol frontalde ve serebellar orta hatta büyük kistik kitle lezyonlarý tespit edildi. Yapýlan PET-CT (Pozitron Emisyon Tomografi) incelemesinde, baþka herhangi bir organýnda metastaz tespit edilmedi. Meme açýsýndan yapýlan genel cerrahi konsültasyonunda herhangi bir patoloji bulunmadý. Her iki kranial lezyon nedeniyle bir hafta arayla iki kez ameliyat edilen olgunun yapýlan patolojik incelemesinde, kistik meme kanseri metastazý tespit edildi. Ameliyat sonrasýnda olguya tüm beyin radyoterapi uygulandý. Kemoterapi uygulanmadý. Bu olgu dolayýsýyla kranial kistik metastazlarda, ender de rastlansa meme kanseri metastazlarýný ayýrýcý tanýda düþünmemiz gerektiðini vurgulamak istedik.