Metakronöz Timoma ve Küçük Hücreli Dýþý Akciðer Kanserli Bîr Olgu Sunumu

Various cancers (lung, colon, soft tissue, digestive system ete.) have been reported as second malignaney in about 15 percent of patients with thymoma. A 44 year old man who has mediastinal mass was performed left toracotomy and mass excision and diagnosed as mixt type thymoma and capsule invasion. After the patient was referred to our ctinic for postoperative radiotherapy and was evaluated as stage 2. Total dose of 56 Gy was planned to mediasten and primary mass area. Ýn follow-up thorax computerized tomography taken fourth months after radiotherapy was normal and routine Controls were vvithout iitness during six years. Unfortunately six years after radiotherapy fiberoptic broncoscopy was applied from upper lobe of right lung because of dyspnea and hemoptysis and nonsmall celi lung cancer was estabilished. At the same time thorax computerized tomography showed right hilar mass and caviter lesion associated vvith this. Therefore, chemotherapy was planned vvith Cisplatin and Gemcitabin. But the patient ývas lost because of severe hemoptysis before chemotherapy in one month.

Metachronous Thymoma and Nonsmall Celi Lung Cancer A Case Report

Timomalarýn %15 kadarýnda çeþitli kanserler (akciðer, kolon, yumuþak doku, dijestiv sistem gibi) ikincil maligniteler olarak bildirilmiþtir. Mediastinal kitle ön tanýsýyla dýþ merkezde tetkik edilen 44 yaþýndaki erkek hastanýn sol torakotomi + kitle eksizyonu sonrasý patoloji raporu; mikst tip timoma, kapsül invazyonu pozitif olarak rapor edilmiþti. Postoperatif radyoterapi amacýyla kliniðimize refere edilen hasta Evre 2 olarak deðerlendirildi ve mediasten + primer kitle iojuna toplam 56 Gy radyoterapi uygulandý. Takipte radyoterapi sonrasý dördüncü ayda çekilen toraks tomografisinde nüks kitle saptanmayan hastanýn izlemleri 6 yýl boyunca hastalýksýz devam etti. Ancak radyoterapiden altý yýl sonra nefes darlýðý ve hemoptizi yakýnmalarýyla dýþ merkezde sað akciðer üst lobdan yapýlan bronkoskopik biyopsi sonucu; küçük hücreli dýþý akciðer karsinomu gelen hastanýn toraks tomografisinde; sað hilus üst arka komþuluðunda içi hava dolu, sað ana bronþ ile iliþkili kaviter lezyon saptandý. Ardýndan sisplatin + gemsitabin kemoterapisi planlanan hastaya bu aþamada radyoterapi düþünülmedi. Hasta kemoterapi baþlanamadan abondan hemoptizi nedeniyle bir ay içerisinde kaybedildi.