Is Autologous Stem Cell Transplantation a Risk For Divorce in Lymphoma Survivors?

INTRODUCTION: Apart from standard chemotherapy, autologous stem cell transplantation (ASCT) is one of the most effective treatment options in patients with relapse/refractory lymphomas. Lymphoma survivors are thought to experience some difficulties in social life, business life, sexual life and family relations after ASCT. The aim of this study is to investigate the frequency of divorce in patients who underwent ASCT for lymphoma and to evaluate the patient characteristics and the treatment-related factors that may affect the divorce.
METHODS: Patients over 18 years of age with a diagnosis of relapsed or refractory lymphoma who underwent ASCT and in remission were included in the study. The primary endpoint of the study was to evaluate the frequency of divorce after ASCT. The secondary endpoint was to reveal the factors that might be associated with divorce.
RESULTS: The median age of 95 patients included in the study was 50 (21-69 years). Most of the patients were male (n: 72, 75.8%). More than half of the patients (n: 60, 63.1%) were living in the city center and 73 (69.5%) patients were still working after ASCT. Eighty (84.2%) of our patients were still married. The median duration of marriage in these patients was 30.01 years (2.5-48.5 years). Of the 15 (15.7%) single patients, 4 (4.2%) were divorced after ASCT. It was observed that gender, educational status, employment status, place of residence, childbearing and lymphoma type were not associated with divorce rates.
DISCUSSION AND CONCLUSION: In our study, the rate of divorce was found 4.2% in lymphoma survivors treated with ASCT. According to our results, lymphoma type, gender, employment status and educational status were not associated with divorce risk. Family counseling and psychooncology consultation starting from the pre-ASCT period can reduce the frequency of divorce.

Otolog Kök Hücre Nakli Lenfoma Hastalarýnda Boþanma Ýçin Bir Risk Faktörü müdür?

GÝRÝÞ ve AMAÇ: Standart kemoterapi dýþýnda otolog kök hücre nakli (OKHN), relaps/refrakter lenfomalý hastalarda en etkili tedavi seçeneklerinden biridir. Lenfoma tedavisi için OKHN uygulanan hastalarýn sonraki dönemde sosyal yaþamda, iþ hayatýnda, cinsel yaþamda ve aile iliþkilerinde bazý zorluklar yaþadýklarý düþünülmektedir. Bu çalýþmanýn amacý, lenfoma tedavisi için OKHN uygulanan hastalarda boþanma sýklýðýný araþtýrmak ve boþanma üzerinde etkisi olabilecek hasta ve tedavi iliþkili faktörleri deðerlendirmektir.
YÖNTEM ve GEREÇLER: Relaps veya refrakter lenfoma nedeniyle OKHN uygulanan, 18 yaþ üstü ve remisyonda olan hastalar çalýþmaya dahil edildi. Çalýþmanýn birincil sonlaným noktasý OKHN sonrasý boþanma sýklýðýný deðerlendirmek, ikincil sonlaným noktasý ise boþanmayla iliþkilendirilebilecek faktörleri ortaya koymaktý.
BULGULAR: Çalýþmaya dahil edilen 95 hastanýn ortanca yaþý 50 (21-69 yaþ) idi. Hastalarýn çoðu erkekti (n: 72,% 75.8). OKHN yapýlan hastalarýn yarýsýndan fazlasý (n: 60,% 63.1) þehir merkezinde yaþarken, 73 (% 69.5) hasta halen çalýþýyordu. Hastalarýmýzýn 80'i (%84.2) halen evliydi; bu hastalarda ortanca evlilik süresi 30.01 yýl (2.5-48.5 yýl) idi. On beþ (% 15.7) bekar hastadan 4'ü (% 4.2) OHKN'den sonra boþanmýþ hastalardan oluþmaktaydý. Cinsiyet, eðitim durumu, çalýþma durumu, ikamet yeri, çocuk sahibi olma ve lenfoma tipinin boþanma riski ile iliþkisi olmadýðý görüldü.
TARTIÞMA ve SONUÇ: Çalýþmamýzda OKHN uygulanan lenfoma tanýlý hastalarda boþanma oraný% 4,2 olarak bulunmuþtur. Sonuçlarýmýza göre lenfoma tipi, cinsiyeti, çalýþma durumu ve eðitim durumu boþanma riski ile iliþkili deðildi. OKHN öncesi dönemden baþlamak üzere aile danýþmanlýðý verilmesi ve psikoonkoloji konsultasyonunun boþanma sýklýðýný azaltabileceði düþünülmüþtür.