Diabetic Mastopathy and Breast Cancer in Type-2 Diabetes Mellitus Patient: A Case Report

Diabetic mastopathy is a rare inflammatory breast disease demonstrated with ductitis, lymphocytic lobulitis and perivasculitis with stromal fibrosis. This lesion often presents as a discretely palpable uni- or bilateral mass in traditional type I diabetes and other autoimmune diseases. We report a case of diabetic mastopathy, which presented clinically as an indeterminate breast lump suspicious for malignancy. The patient is a 74-year-old woman who had type 2 diabetes mellitus. Mammography and ultrasonography raised a suspicion of malignancy, and a wire-guided excisional biopsy was performed. The biopsy was reported as invasive carcinoma. Histopathological examination now showed dense keloid-like stromal fibrosis with lymphoid features consistent with diabetic mastopathy.

Tip 2 Diyabetli Hastada Diyabetik Mastopati ve Meme Kanseri: Olgu Sunumu

Diyabetik mastopati; lenfositik lobulit, duktit ve stromal fibrozisli perivaskülit tablosuyla karakterize nadir görülen bir fibroinflamatuar meme hastalýðýdýr. Bu meme lezyonu uzun süreli tip 1 diyabet ve diðer otoimmün hastalýklarý olanlarda, genellikle unilateral veya bilateral palpe edilebilir. Memede kitle ile baþvuran ve kliniði malign olan diyabetik mastopatili hastayý raporluyoruz. Bu tip 2 diyabetli hastamýz 74 yaþýndadýr. Mamografisi ve ultrasonografisi malignite þüphesi uyandýrdýðýndan bu hastaya tel yardýmýyla eksizyonel biyopsi uygulandý. Biyopsi sonucu invaziv karsinom olarak raporlandý. Bu biyopsi sonucuyla yapýlan operasyon sonrasý patoloji raporunda ise yoðun keloid benzeri stromal fibrozisin eþlik ettiði lenfoid deðiþimlerin diyabetik mastopati ile uyumlu olduðu bildirildi.