Abstract

Lymphoma of the female genital tract (FGT) is uncommon. This diagnosis, in such an unusual location, is very difficult to estabiish. Herein ıve report a case of FGT lymphoma and describe it’s ıvay to diagnosis. A 37 year-old-woman vvas referred to our institution due to undiagnosed cervical mass. Two consecutive biopsies had been taken from the mass, both of vvhich yieid-ed infiamation. An unusual-looking bulky cervical mass vvas seen and the upper part of vagina and parametriai tissues vvere deeply infiltrated. On magnetic resonance imaging a uterine mass measuring 7.0 cm x 8.8 cm x 2.3 cm ıvas protruding into the vagina. A pathologic sized lymph node in the left iliac region vvas detected. The vaginal vvall vvas thickened, 3.3 cm in diameter. Punch biopsy vvas reported as regenerative changes. After that a core biopsy vvas taken from a different area on the mass, from vvhich biopsy ıvas not taken before. Histopathological analysis retrieved a diffuse large celi non-Hodgkin’s lymphoma according to REAL classification. Computed tomography (CT) and flourodeoxyglucose-18 positron emission tomography (FDG-PET) vvas used for staging. According to Ann Arbor staging system, stage vvas lleb and after 6 courses of R-CHOP and additional 2 cours-es of rituximab therapy, patient is on complete remission. İn case of peivic masses vvith negative biopsy results, core biopsy should be preferred instead of using punch or excisional method. Uterine lymphomas may be easily masked by infiamation or misdiagnosed as infiamation unless it is not suspected. Probably using both CT and FDG-PET is the best for proper staging.