Abstract

INTRODUCTION

The aim of this study is to present clinical-radiological characteristics, pathological correlation and surgical results of 87 patients in whom stereotactic brain biopsy was performed.

METHODS

Radiological workup, patient charts and pathological diagnoses of 87 patients who had stereotactic brain biopsy for various intracerebral lesions between January 2013 and June 2018 were retrospectively reviewed. Diagnotic yield, concordance between histopathological diagnoses, radiological presumptive diagnoses and frozen section results were identified. Procedural complicaiton rates were determined and descriptive statistical data was presented. Risk factors that may be associated with the procedure were evaluated with inferential statistical tools.

RESULTS

Diagnostic yield of procedures was 92%. Overall 71.3% of presumptive radiologic diagnoses and 63.3% of intraoperative consultation results were in accordance with final histopathologic diagnosis. Most commonly encountered diagnosis was central nervous system lymphoma. Procedure related mortality rate was 0%, whereas procedure related complication rate was 9.2%. Most common complication was bleeding at biopsy site. Only the deep seated biopsy site was marginally significant risk factor for bleeding among other possible risk factors.(p=0.066).

DISCUSSION AND CONCLUSION

Stereotactic brain biopsy is still a reliable tool with high diagnostic yield and relative low mortality and morbidity rates.