Abstract

Advanced cancers frequently metastasise to the bone, and the resulting bone destruction is associated with a variety of skeletal complications, including pathologic fractures, bone pain, impaired mobility and spinal cord compression. Bone metastases are distant relapses from many types of malignant tumours, especially from cancers of the lung, breast, and prostate Direct invasion by tumor and lymphatic and hematogenous metastases to the bone occur. Technetium (Tc 99m) bone scintigraphy and direct radiographs are widely regarded. Computed tomography, magnetic resonance imaging and positron emission tomography are useful tools for diagnosis and treatment. Present treatment options for patients with bone metastases include radiation therapy, surgery, bisphosphonates, radionuclides and analgesics, in addition to Standard anticancer therapy. The primary goal of therapy is to minimise bone pain and morbidity and improve mobility and quality of life. Single fraction radiotherapy (RT) is as safe and effective as a multifraction regimen for the palliation of metastatic bone pain. The greater convenience for the patients and the department single fraction RT is preferred.