Abstract

Inflammatory breast cancer (IBC) is the %1-6of breast cancer and had a worse prognosis than locally advanced breast cancer. Forty-one patients with IBC were analysed retrospectively. Disease free sun/ival (DFS), overall survival (OS), prognostic fac-tors were evaluated by univariety analysis. Median age of patients was 46. After the diagnosis, 28 patients underwent mastectomy. Median two cycles of neoadjuvant chemotherapy (CT) was given to 51% patients. Taxanes and antracyclines included regi-mens were given as adjuvant CT and also adjuvant radiotherapy was given 66% of patients. For the 19 months of follow-up time, three years OS and DFS rates were 81% and 49.8% respectively. Median DFS was 28.8 months, median OS was not reached. We found that neoadjuvant CT was related OS, perineural invasion, c-erbB2 expression was related with DFS by univariety analysis (p< 0.05). Hovevver, there was not any prognostic factor related survival by multivariety analysis. IBC stili has bad prognosis, larger studies with more patients are needed.