Abstract

Purpose: Hematological disorders are the most common indications for performing splenectomy after trauma in adults. The aim of this study is to investigate the treatment outcomes of splenectomy in hematological malignancy patients who were operated between the years 1998 and 2009. Patients and Methods: We analyzed the patients’ clinical characteristics, type of surgical treatment, preoperative and postoperative medical treatments, complications and thrombocyte responses, retrospectively. Results: Seventeen male and 13 female patients, with a mean age of 50.7 (17-79), underwent splenectomy due to following indications: Hodgkin lymphoma (n=10), Non Hodgkin lymphoma (n=12), Chronic Lymphocytic lymphoma (n=5), MALT lymphoma (n=2) and Hairy Cell Leukemia (n=1). The indications for surgery was splenomegaly and its complications (n=20), gastric obstruction (n= 5), diagnosis splenic mass (n=3), major bleeding (n=1) and abscess (n=1). Complications related to surgery occurred in 10 patients: pneumonia (n=6), bleeding (n=2), abscess (n=1) and sepsis (n=1). Early 30-day mortality was observed in two cases. During the follow-up period, platelet value revealed response in 19 (63.3 %), partial response in 8 (26.7 %) and unresponsive in 3 (10 %) patients due to splenectomy. Conclusion: In conclusion; for hematological diseases, thrombocytopenia, massive splenomegaly and its complications, splenectomy is a safe method with acceptable complications rate and improves the patients’ survival outcomes.