Effects of Tamoxifen on Premenopausal Breast Cancer Patients in Terms of Anxiety, Depression, Quality of Life and Sexual Satisfaction
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Original Article
P: 1-8
2014

Effects of Tamoxifen on Premenopausal Breast Cancer Patients in Terms of Anxiety, Depression, Quality of Life and Sexual Satisfaction

Acta Haematol Oncol Turc 2014;47(3):1-8
1. Izmir Katip Celebi University, Ataturk Training And Research Hospital, Department Of Medical Oncology, Izmir, Turkey
2. Dokuz Eylul University, Faculty Of Medicine, Department Of Hematology, Izmir, Turkey
3.
No information available.
No information available
Received Date: 2014-09-29T14:03:05
Accepted Date: 2015-02-27T09:29:03
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Abstract

OBJECTIVE

In this study, we aimed to determine the effects of tamoxifen on premenopausal breast cancer patients in terms of anxiety, depression, quality of life (QoL) and sexual satisfaction.

METHODS

Sixty-seven premenopausal breast cancer women using adjuvant tamoxifen were participated in the study and the data were collected using a series of forms completed during face-to-face interviews. The form that consists of socio-demographic characteristics of the pateints, the Hospital Anxiety and Depression Scale (HADS), Golombok-Rust Inventory of Sexual Satisfaction (GRISS) and European Organization for Research on Treatment of Cancer Questionnaires Quality of Life-C30 (EORTC-QoL-C30) were applied to the participants.

RESULTS

We determined that 46.26% of the patients had depression and 40.29% had high anxiety levels. Physical, role, cognitive, emotional and social functioning and global QoL subscores were also found to be low in patients whose anxiety levels were high. In patients whose depression scores were high, all the functioning scales, except physical functioning scale and global QoL subscores of EORTC-QLQ-C30 were found statistically significantly low. All the GRISS subscores were higher in the patients whose anxiety levels were high. However, statistical significance was observed only in the communication, satisfaction, touch and anorgasmi subscores. All the GRISS subscores were higher in the patients who had high depression level. But the statistical significance was found only in communication, satisfaction, touch and anorgasmi subscores.

CONCLUSION

Breast cancer and its long-term adjuvant treatments affect not only the patients’ clinical status but also their psychosocial and psychosexual aspects. Therefore, being aware of these aspects and management of them may increase the quality of life of breast cancer patients.