Abstract

INTRODUCTION

The present study aimed to compare early complication rates, risk factors for complications, and hospital stay lengths in patients operated on for Colorectal cancer, by using Clavien-Dindo and Common Terminology Criteria for Adverse Events (CTCAE) complication classifications.

METHODS

222 patients who were operated between March 2019 and June 2020 with the diagnosis of colorectal cancer and had early complications were evaluated retrospectively.Patients who were operated with the diagnosis of colorectal cancer and who developed early complications in their clinical follow-up were included in the present study. Patients who were operated for colorectal malignancy relapse, patients younger than 18 years of age, patients considered inoperable in the intraoperative evaluation, and pregnant women were excluded from the study.Complications that developed in the postoperative period were graded according to Clavien-Dindo and CTCAE classifications.

RESULTS

According to the Clavien-Dindo classification, there were 161 patients (72.5%) in grade I, 13 patients (5.9%) in grade II, 14 patients (6.3%) in grade IIIA, 20 patients (9%) in grade IIIB, 11 patients (4.9%) in grade IVA and 3 patients (1.4%) in grade V, in terms of development of complications. According to the CTCAE classification in terms of complication development, 162 (73%) patients with grade II, 36 (16.2%) patients with grade III, 21 (9.5%) patients with grade IV and 3 patients with grade V (1.4%) were reported. According to the Clavien-Dindo classification, the risk of developing complications was 3 times higher in male gender, 8 times higher in open surgical intervention, and 1.7 times higher in diabetes mellitus. According to the CTCAE classification, performing liver resection in the same session increased the risk of complications 5 times, while the use of open surgical technique increased the risk 8 times.

DISCUSSION AND CONCLUSION

: Neither classification system is superior to the other in grading postoperative complications, and both can be used to rate surgical complications.