Effect of hyponatremia on muscle mass and interdialytic weight gain in haemodialysis patients
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Original Article
VOLUME: 53 ISSUE: 1
P: 17 - 23
2020

Effect of hyponatremia on muscle mass and interdialytic weight gain in haemodialysis patients

Acta Haematol Oncol Turc 2020;53(1):17-23
1. Diskapi Yildirim Beyazit Training and Research Hospital Nephrology Department Ankara/ Turkey
2. Gazi University Faculty of Health Sciences Department of Nutrition and Dietetics Ankara/ Turkey
3. Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital Ankara/ Turkey
4.
No information available.
No information available
Received Date: 18.12.2019
Accepted Date: 28.04.2020
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Abstract

INTRODUCTION

Objective: We evaluated the relationship between the pre-dialytic serum sodium value and malnutrition, the parameters of evaluating the muscular function, muscular mass or interdialytic weight gain.

METHODS

Material and Method: 150 haemodialysis patients were included in the study planned to be cross-sectional. In the evaluation; malnutrition-inflammation score, handgrip strength, mid arm circumference, triceps skinfold, mid arm muscle circumference, and bioelectrical-impedance analysis (fat percent, fat free mass, basal metabolism rate, body mass index, total body water) were considered and examined. The six-month average of the pre-dialytic serum sodium value, which is considered monthly, was taken. The patients under the average value of 136.84 mEq/L pre-dialytic serum sodium value were included in the Group 1 and those above it were included in the Group 2. Serum albumin, C-reactive protein and the other monthly routine laboratory examinations were taken from the patient’s follow-up file. Interdialytic weight gain was calculated by extracting the patient’s post-dialysis weight from the patient’s pre-dialytic weight.

RESULTS

Results: The only significant difference between the two groups concordant according to the age and sex was interdialytic weight gain (p < 0.001). In the analysis, there was a significant relationship (p < 0.001) and inverse correlation (r= -0.311, p < 0.001) between pre-dialytic serum sodium value and interdialytic weight gain.

DISCUSSION AND CONCLUSION

Conclusion: No relationship was found between the pre-dialytic serum sodium value of the haemodialysis patients and inflammation, malnutrition and anthropometric measurements. There was a negative correlation between the pre-dialytic serum sodium value and interdialytic weight gain, and it was statistically significant.

Keywords:
Haemodialysis, hyponatremia, interdialytic weight gain, muscle mass