Bir Akut Promiyelositik Lösemi Olgusunda “All-Trans Retinoic Acid (ATRA)” Tedavisi Sırasında Ağrısız Skrotal Ülser
PDF
Cite
Share
Request
P: 24-26
2009

Bir Akut Promiyelositik Lösemi Olgusunda “All-Trans Retinoic Acid (ATRA)” Tedavisi Sırasında Ağrısız Skrotal Ülser

Acta Haematol Oncol Turc 2009;42(1):24-26
1. Ankara Üniversitesi Tıp Fakültesi Hematoloji Bölümü,
2. SB Dr. Abdurrahman Yurtarsian Ankara Onkoloji Eğitim ve Araştırma Hastanesi, Hematoloji Bilim Dalı, ANKARA
3.
No information available.
No information available
Received Date: 2014-08-28T17:06:34
PDF
Cite
Share
Request

Abstract

Acute promyelocytic leukemia (APL), acute myeloblastik leukemia (AML) M3 according to FAB classification is a distinct subtype of AML usuaily characterized by hypergranular leukemic cells, bleeding diathesis and a spesific translocation t(15:17) vvhich plays a pivotal role in the pathogenesis of APL. The gold Standard therapy in APL is all-trans retinoic acid (ATRA) containing combinations. Despite possible significant side effects, ATRA is well tolerated. We report on a 50-year-old man vvith APL who developed scrotal ulcerations during treatment vvith ATRA. Although there are few case reports, to our knovvledge this case is the first one that has painless scrotal ulcerations related vvith ATRA.

Keywords:
Acute promyelocytic leukemia
all-trans retinoic acid
scrotal ulcer.