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Benign peripheral nerve sheath tumors of the extremities: a study of one hundred patients.
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Original Article
VOLUME: 53 ISSUE: 1
P: 94-101
2020

Benign peripheral nerve sheath tumors of the extremities: a study of one hundred patients.

Acta Haematol Oncol Turc 2020;53(1):94-101
DOI: 10.5505/aot.2020.07641
Hüseyin Bilgehan Çevik 1
Sibel Kayahan 2
Engin Eceviz 3
Seyit Ali Gümüştaş 3
1. Department of Orthopaedics and Traumatology, Dışkapı Yıldırım Beyazıt Research and Training Hospital, Ankara, Turkey
2. Department of Pathology, Kartal Dr. Lütfi Kırdar Research and Training Hospital, İstanbul, Turkey
3. Department of Orthopaedics and Traumatology, Kartal Dr. Lütfi Kırdar Research and Training Hospital, İstanbul, Turkey
4.
No information available.
No information available
Received Date: 2019-11-19T10:25:32
Accepted Date: 2020-04-28T11:18:47
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Abstract

INTRODUCTION

Benign peripheral nerve sheath tumors (BPNST) are common tumors, with challenging management. The main target of surgical management of BPNSTs is excision of the tumor with preservation of neurological functions. The aim of the present study was to investigate the demographic features, clinical presentations, surgical and pathological findings, and outcomes of BPNSTs in respect of morbidity.

METHODS

A retrospective analysis of clinical and radiological findings of 100 patients with BPNSTs involving the extremities who were surgically treated at our tertiary hospital center, between 2006 and 2016.

RESULTS

In this series, evaluation was made of 100 patients comprising 52 males and 48 females with 55 schwannomas, 38 neurofibromas, 5 plexiform neurofibromas, and 2 plexiform schwannomas. The most presenting feature was painful mass. A pre-operative biopsy was performed in 20 patients with suspicion of malignancy. Of these 20 patients, 6 had post-operative motor deficits and 7 had continuous pain in the follow-up period. Recurrence was seen in 5% (5/100) patients. There were 23% patients (23/100) with BPNSTs were associated with NF type-1. The overall average follow-up was 77 months.

DISCUSSION AND CONCLUSION

BPNSTs have great clinical outcome with total excision of the tumor. BPNSTs are tumors that can be seen at any age, and generally they are presented with a palpable mass. Most of the BPNSTs are schwannomas. Orthopedic surgeons should in mind the possible nerve damage caused by a biopsy and/or surgery. Considering the balance between malignancy suspicion and possible nerve damage, biopsy should be planned carefully.