EN | TR
E-ISSN: 3061-9947
Are the erythrocyte distribution width, mean erythrocyte volume and neutrophil/lymphocye ratio predictive values in the evaluation the response of treatment in locally advanced non small cell lung cancer?
PDF
Cite
Share
Request
Original Article
VOLUME: 51 ISSUE: 3
P: 348-352
2018

Are the erythrocyte distribution width, mean erythrocyte volume and neutrophil/lymphocye ratio predictive values in the evaluation the response of treatment in locally advanced non small cell lung cancer?

Acta Haematol Oncol Turc 2018;51(3):348-352
DOI: 10.5505/aot.2018.27879
Tolga Köşeci 1
Ömer Kaya 2
Veysel Haksöyler 3
Ali Murat Sedef 4
1. Hatay State Hospital Medical Ocology Department, Hatay, Turkey
2. Ceyhan State Hospital Radiology Department, Adana, Turkey
3. University of Health Sciences Gazi Yaşargil Training and Research Hospital, Medical Oncology Depatment, Diyarbakır, Turkey
4. Tarsus Medical Park Hospital Medical Oncology Department, Mersin, Turkey
5.
No information available.
No information available
Received Date: 2018-12-16T13:15:50
Accepted Date: 2018-12-28T09:17:39
PDF
Cite
Share
Request

Abstract

INTRODUCTION

We investigated whether the mean platelet volume, erythrocyte distribution width and neutrophil / lymphocyte ratio can be a predictive values for the evaluation of tumor size response after treatment in patients with local advanced non-small cell lung carcinoma.

METHODS

The data of 39 patients with local advanced (stage III) non-small cell lung carcinoma who had received chemoradiotherapy treatment were retrospectively reviewed., Neutrophil, lymphocyte, mean erythrocyte volume, erythrocyte distribution width datas which noted before and after treatment were evaluated. In addition, pre and post-treatment the primary tumor size and the suv-max values of these lesions were recorded which is noted in positron emission tomography (PET-CT) reports

RESULTS

The mean age of the patients was 61 (range 43-78), 38 patients were male and 1 were female. The number of patients with partial response to treatment was 22 and with stable response was 17. Twenty-one patients had squamous cell carcinoma (53.8%) and 18 (46.2%) had adenocarcinoma. Cut-off values were 2.99 for neutrophil / lymphocyte ratio, 14.65 for erythrocyte distribution width and 9.5 for mean platelet volume. The cut-off values for each of the three parameters were not statistically significant

DISCUSSION AND CONCLUSION

In patients who received chemoradiotherapy treatment for local advanced lung carcinoma, a predictive value could not be obtained within the parameters evaluated in response of treatment.