Anastrazol Tedavisi Altında İzole Över Metastazı ile Saptanan Nüks Meme Kanseri Olgusu
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P: 42-45
2010

Anastrazol Tedavisi Altında İzole Över Metastazı ile Saptanan Nüks Meme Kanseri Olgusu

Acta Haematol Oncol Turc 2010;43(1):42-45
1. Dr. Lütfi Kırçlar Kartal Eğitim ve Araştırma Hastanesi, Tıbbi Onkoloji Kliniği,
2. Dr. Lütfi Kırdar Kartal Eğitim ve Araştırma Hastanesi, Patoloji Kliniği, İSTANBUL
3.
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Received Date: 2014-08-28T17:06:36
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Abstract

Ovarian metastases originate from mostly genital organ, aftervvards gastrointestinal tract and breast carcinoma, respectively. İn this report, we present a case of recurrent breast cancer who vvas diagnosed vvith isolated ovarian metastases seven years after the diagnosis of breast cancer and had treated vvith adjuvant chemotherapy and vvere followed-up under anastrozole treatment. She vvas presented vvith abdominal pain at the right lovver side. Radiological examinations revealed a mass vvhich vvas similar to uterine leiomyoma in the uterus. A total hysterectomy vvith bilateral salpingo-oopherectomy vvas performed. Histopathologic examination of specimen revealed carcinoma infiltration of the right ovary. İn immunohistochemical staining the diffuse and strong positivity vvith cytokeratin (CK) 7 and gross cyctic disease fluid protein (GCDFP-15) vvere detected. The diagnosis of invasive ductal breast carcinoma to the right ovary vvas made by morphological, IHC and clinical findings. She vvas received four cycles chemotherapy, postoperatively. The patient vvas follovved-up vvithout relapse vvithin 21 months under hormonotherapy. İn patients vvith breast cancer, when a mass is detected in ovaries or pelvic region, not only primary ovarian cancer, but metastatic breast carcinoma to ovaries should be kept in mind.