A comparative study of artificial bone graft versus allograft in the reconstruction of defects after benign tumor curettage.
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Original Article
P: 151-158
2018

A comparative study of artificial bone graft versus allograft in the reconstruction of defects after benign tumor curettage.

Acta Haematol Oncol Turc 2018;51(2):151-158
1. Memorial Diyarbakır Hospital, Orthopedics and Traumatology, Diyarbakır
2. Dortyol State Hospital, Orthopedics and Traumatology, Hatay
3. Polatlı State Hospital, Orthopedics and Traumatology, Ankara
4.
No information available.
No information available
Received Date: 2017-11-14T01:02:41
Accepted Date: 2018-08-16T09:39:42
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Abstract

INTRODUCTION

Bone is a complex and specialized connective tisssue. However, bone defects caused by trauma, infection and tumors sometimes may not heal with bone tissue. In such cases, bone defects may need to be filled with bone graft materials to facilitate or start healing. In this study, we aimed to evaluate the bone healing rates of grafted defects with synthetic bone grafts and cancellous allografts in benign bone tumors.

METHODS

The union rates between synthetic bone grafts (beta tricalcium phosphate) and cancellous allografts used in patients who were diagnosed benign bone tumor treated surgically in Dr.A.Y.Ankara Oncology Training and Research Hospita lOrthopedics and Traumatology Clinic between 2009 and 2013. The cases were evaluated retrospectively and 26 patients were included for both groups.

RESULTS

The mean duration of graft union was 149.26 days in patients using synthetic grafts and 103.35 days in patients using cancellous grafts. The mean duration of union was 125.38 days in patients under 20 years of age and 124.35 days in patients 21 years and older. There is a statistically significant difference in the duraton of graft union between the patients with synthetic grafts and those with cancellous allografts (p <0.05).

DISCUSSION AND CONCLUSION

Benign bone tumors are usually treated with curettage of the cavity, adjuvant application in aggressive tumors, and filling of resulting defect. Today, polymethylmethacrylate, synthetic bone grafts, allografts and autografts are used to fill the defect. Allografts have risk of infectious diseases,deep infection and usually change their biological properties after prepared. In autografts, donor site morbidity exists and sources are limited. Some authors suggest leaving the defects empty, but this can lead to premature fractures or collapse. To avoid these limitations, the use of synthetic bone grafts has become popular, but as a result of this study, beta-tricalcium phosphate as a synthetic allograft has been healed later than cancellous allografts.

Keywords:
benign bone tumors
allograft
synthetic bone graft