A Case of Metastatic Malignant Melanoma who Lung Progressed During Vemurafenib Treatment
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Case report
P: 50-52
2013

A Case of Metastatic Malignant Melanoma who Lung Progressed During Vemurafenib Treatment

Acta Haematol Oncol Turc 2013;46(1):50-52
1. Dr A. Y Ankara Oncology Training And Researh Hospital Department Of Medical Oncology, Ankara, Turkey
2. Gaziosmanpasa University, Faculty Of Medicine, Department Of Medical Oncology, Tokat, Turkey
3.
No information available.
No information available
Received Date: 2014-08-02T11:47:13
Accepted Date: 2015-04-27T13:50:23
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Abstract

A 70 year-old women admitted to our hospital with a swelling and discharge of the right inguinal site. Biopsy results was consisted with malignant melanoma. Imaging of thorax and abdomen showed metastatic disease. After first-line temozolamide treatment, palliative radiotherapy was applied to primary site because of progression. After detection of BRAF-V600E mutation, vemurafenib treatment was initiated. Treatment response to vemurafenib was very good partial response after second months of the treatment. Although locally progression of the left lung was seen after fifth months of therapy, partial response remained on the other sites, she was still on the treatment with vemurafenib.

Keywords:
Malignant Melanoma
Vemurafenib
Radiotherapy