Sinusoidal Obstruction Syndrome during oxaliplatin based chemotherapy treatment.
PDF

Case report

Sinusoidal Obstruction Syndrome during oxaliplatin based chemotherapy treatment.

Acta Haematol Oncol Turc 2018;51(2):256-258 DOI: 10.5505/aot.2018.63835
, ,
PDF
Permissions

Abstract

Oxaliplatin is a commonly used chemotherapeutic agent in our oncology daily practice.Neurotoxicity is the most common side effect associated with oxaliplatin therapy.Rarely, oxaliplatin therapy can cause veno-occlusive disease in the liver sinusoids, leading to obstruction and portal hypertension. Weight gain, right upper quadrant pain, ascites, hepatic insufficiency, liver failure can be seen in patients. We presented a clinical course of venoocclusive disease, which developed in third stage colonic cancer, treated with capecitabine and oxaliplatin as adjuvant treatment.

Keywords: Oxaliplatin, Sinusoidal Obstruction Syndrome, Ascites