ATYPICAL PRESENTATION IN LANGERHANS CELL HISTIOCYTOSIS: Hearing Loss, Diabetes Insipidus, & Extensive Cutaneous Lesions with Nail Distrophy
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Case report

ATYPICAL PRESENTATION IN LANGERHANS CELL HISTIOCYTOSIS: Hearing Loss, Diabetes Insipidus, & Extensive Cutaneous Lesions with Nail Distrophy

Acta Haematol Oncol Turc 2017;50(1):76-80 DOI: 10.5505/aot.2017.70299
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Abstract

Langerhans cell histiocytosis (LCH) is a clonal proliferative lymphohistiocytic disorder with mainly CD-1a positive staining. It has a wide spectrum of unifocal or multifocal mono or multisystemic disease. Rare symptoms like diabetes insipidus, hearing loss or nail distrophy might also occur according to the involved sites. In here, two cases of LCH with atypical presentation are reported with review of the literature.

Keywords: Langerhans cell histiocytosis, diabetes insipidus, hearing loss, nail distrophy