Desmoid Fibromatosis of The Breast; A Case Report

Desmoid-type fibromatosis of the breast is a rare, locally aggressive stromal tumor. This lesion is observed in 0.2% of all breast tumors, often occurs between the ages of 25 and 45 and the sex ratio is 1: 2 (male: female). In this study, we report a case of a 57-year-old woman with breast fibromatosis, which has been mimicking breast carcinoma. On physical examination, there was an irregularly shaped mass lesion of approximately 3x2 cm fixed to the chest wall in the upper outer quadrant of the left breast. On mammography, an increase in opacity covered by fibroglandular tissue was observed in the outer middle part of the left breast. On ultrasound examination, a heterogeneous hypoechoic solid lesion with microcalcifications in places and 32x10mm in size with irregular borders and internal echoes were observed in the upper outer quadrant of the left breast. (BIRADS 4). Since the tru-cut biopsy could not differentiate between Fibromatosis-like Metaplastic Breast Carcinoma and Desmoid Fibromatosis, an excisional biopsy was performed under general anaesthesia. Wide local excision was performed due to positive surgical margins. In conclusion, desmoid-type fibromatosis has nonspecific physical examination findings and radiological imaging and is confused with malignancy. The primary treatment of this lesion is excision with a negative surgical margin

Memenin Desmoid Fibromatozisi; Olgu Sunumu

Memenin desmoid tip fibromatozisi nadir görülen, lokal agresif bir stromal tümördür. Bu lezyon tüm meme tümörlerinin %0,2'sinde görülür, sýklýkla 25-45 yaþlarý arasýnda ortaya çýkar ve erkek: kadýn oraný 1: 2'dir. Bu olgu sunumunda, meme kanserini taklit eden meme fibromatozisi olan 57 yaþýnda bir kadýn hastayý sunuyoruz. Fizik muayenede sol meme üst dýþ kadranda göðüs duvarýna fikse yaklaþýk 3x2 cm boyutlarýnda düzensiz þekilli kitle lezyonu izlendi. Mamografide sol meme dýþ orta kýsmýnda fibroglandüler doku ile örtülü opaklýkta artýþ izlendi. Ultrason muayenesinde sol meme üst dýþ kadranda 32x10mm boyutlarýnda, sýnýrlarý düzensiz, iç ekosu olan, yer yer mikrokalsifikasyonlu, heterojen hipoekoik solid lezyon izlendi. (BIRADS 4). Tru-cut biyopside fibromatozis benzeri metaplastik meme karsinomu ile desmoid fibromatozis ayýrt edilemediðinden genel anestezi altýnda eksizyonel biyopsi gerçekleþtirildi. Pozitif cerrahi sýnýrlar nedeniyle geniþ lokal eksizyon uygulandý. Sonuç olarak, desmoid tip fibromatosis nonspesifik fizik muayene bulgularý ve radyolojik görüntüleme bulgularýna sahiptir ve malignite ile karýþtýrýlmaktadýr. Bu lezyonun primer tedavisi negatif cerrahi sýnýr ile eksizyondur.