Primary Cardiac Angiosarcoma: A Case Report

Primary cardiac angiosarcoma is a rare disease with poor prognosis. A 34-year-old male patient who underwent an open cardiac surgery and diagnosed as cardiac angiosarcoma on the right atrium was admitted to the medical oncology department. Complete curative resection of the tumor was not possible and postoperatively 6 cycles of combination chemotherapy regimen (ifosphamide with mesna protection and doxorubicin) was given. Patient had stable disease for 8 months, and after progression a second-line chemotherapy (paclitaxel) was started but he died after 15 months of diagnosis. Since curative resections are not possible in most of the cardiac angiosarcoma cases, further treatment options are desperately needed.

Primer Kardiyak Anjiosarkoma: Bir Olgu Sunumu

Primer kardiyak anjiosarkoma, kötü prognozlu nadir bir hastalýktýr. Açýk kardiyak cerrahi operasyon olan ve sað atriumda kardiyak anjiosarkoma tanýsý alan 34 yaþýnda erkek hasta týbbi onkoloji bölümüne baþvurdu. Tümörün tam küratif rezeksiyonu mümkün olmamýþtý ve hastaya postoperatif dönemde 6 siklus kombinasyon kemoterapi rejimen (doksorubisin ve mesna korumasýyla ifosfamid) verildi. Hastada 8 ay boyunca stabil hastalýk mevcuttu, ve progresyon sonrasýnda ikinci sýra kemoterapi (paklitaksel) baþlandý, ancak hasta tanýdan 15 ay sonra kaybedildi. Kardiyak anjiosarkoma olgularýnýn çoðunda küratif rezeksiyonlar mümkün olmadýðýndan daha ileri tedavi seçeneklerine son derece ihtiyaç vardýr.