Tiroid Nodüllerinin Ýnce Ýðne Aspirasyon Biyopsisinde 21 G ve 22 G Enjektör Ýðnelerinin Karþýlaþtýrýlmasý*

To compare cytological betvveen 21 G and 22 G injector needles in the US-guided fine-needle aspiration biopsy (FNAB) met-hod of thyroid gland nodules forms the basis of our study. We statistically evaluated cytological results of 102 FNAB performed vvith 21 G (green) needles betvveen 2005 September-2006 January (Group 1) and 136 FNAB vvith 22 G (black) needles betvveen 2006 February-2006 May (Group 2). The rates of maügnant (positive)/berýign (negative) were not different between Group 1 and Group 2 (p= 0.292). Age, gender, performers of FNAB, injectors used, size and features of nodules were similarat eithergroup (p> 0.05). The patients whose biopsy results were blood elements and non-diagnostic and who were found false positive or faise negative at follow-up were accepted unsuccess-ful, whereas the patients who were true positive or true negative were successful. Analysis was performed in both conditions where the patients diagnosed as suspected maiignant were included/excluded. Success was compared betvveen both needle groups. The mean age of the patients and male/women ratio were 47.5 ± 12.3 years (46.8 ± 12.5 in Group 1, 48.0 ± 12.2 in Group 2) and 30.8% (37.8% in Group 1, 25.9% in Group 2) respectiveiy. 15.1% (13 cases) of Group 1 was unsuccessful and 84.9% (73 cases) successful; whereas 8.3%> (10 cases) of Group 2 was unsuccessful and 91.7% (110 cases) successful. Although Group 2 was more successful; the statistical difference was not significant betvveen 2 groups (p= 0.127). The result was the same in including of suspected maiignant cases (p=0.102). Ýn total 238 cases, 87.4% in accuracy, 100% in positive predictive value, and 85.0% in negative predictive value were found. No complication was observed in either group. Success rate percent, despite not significant statistical difference, in the cases of thyroid FNAB vvith 22 G needles (black) was higher than that vvith 21 G needles (green). To compare 21 G or 22 G needles vvith the thinner needles can make significant increase in the success rate statistically.

The Comparison Betvveen 21 G and 22 G Injector Needles in the Fine-Needle Aspiration Biopsy of Thyroid Nodules

Tiroid bezi nodüllerinin US kýlavuzluðundaki ince iðne aspirasyon biyopsisi (ÝÝAB) yönteminde, 21 G ve 22 G enjektör iðnelerinin sitolojik açýdan karþýlaþtýrýlmasý, çalýþmamýzýn amacýný oluþturmaktadýr. Eylül 2005-Ocak 2006 tarihleri arasýnda yeþil uçlu 21 G iðne ile yapýlan 102 adet ÝÝAB’nin (Grup 1), Þubat 2006-Mayýs 2006 tarihleri arasýnda siyah uçlu 22 G iðne ile yapýlan 136 ÝÝAB'nin (Grup 2) sitolojik sonuçlarýný istatistiksel olarak inceledik. Olgularýn malign (pozitifj/benign (negatif) oranlarý Grup 1 ile Grup 2 arasýnda farklý deðildi (p= 0.292). Yaþ, cinsiyet, biyopsiyi yapanlar, kullanýlan enjektörler, nodul boyutu ve özellikleri her iki grupta benzerdi (p> 0.05). Biyopsi sonuçlarý kan elemanlarý ve yetersiz materyal gelen olgular ile yalancý pozitif veya negatif olduðu takibinde anlaþýlan olgular baþarýsýz, doðru pozitif ve negatif çýkan olgular ise baþarýlý kabul edildi. Þüpheli malign sonucu gelenler dahil/hariç tutularak her iki durumda analiz yapýlmýþtýr, iðne gruplan arasýndaki baþarý karþýlaþtýrýlmýþým Olgularýn yaþ ortalamasý 47.5 ± 12.3 yaþ (Grup 1 ’de 46.8 ± 12.5, Grup 2’de 48.0 ± 12.2), erkek/kadm olgu %30.8 (Grup 1 ’de %37.8, Grup 2’de %25.9) idi. Deðerlendirmeye alýnan Grup 1 olgularýnýn %15.11 (13 olgu) baþarýsýz, %84.9’u (73 olgu) baþarýlý, Grup 2 olgularýnýn %8.3'ü (10 olgu) baþarýsýz, %91.7’si (110 olgu) baþarýlý bulunmuþtur. Grup 2 daha baþarýlý olmasýna karþýn, 2 grup arasýnda istatistiksel fark anlamlý bulunmamýþtýr (p= 0.127). Þüpheli malign olgular da dahil edildiðinde sonuç deðiþmemiþtir (p= 0.102). Toplam 238 olguda, genel doðruluk %87.4, pozitif prediktif deðer %100 ve negatif prediktif deðer %85.0 bulunmuþtur. Komplikasyon her iki grupta da görülmemiþtir. Tiroid bezi ÝÝAB’sinde 22 G siyah uçlu iðne ile 21 G yeþil uçlu iðne olgularýna göre yüzde baþarý oraný, istatistiksel fark önemli olmamasýna karþýn, daha fazla bulunmuþtur. 21 G veya 22 G iðne ile daha ince iðne karþýlaþtýrmasý, baþarý oranýný istatistiksel olarak anlamlý derecede artýrabilir.