Isolated Leptomeningeal Carcinomatosis in a Patient with Newly Diagnosed Gastric Cancer

A 43 year-old man admitted with abdominal pain and hematemesis. He diagnosed with gastric cancer by endoscopic biopsy and total gastrectomy was carried out. On the sixth day of gastrectomy he complained about headache and diplopia. Magnetic resonance imaging of the brain showed leptomeningeal thickening and contrast enhancement of bilateral cerebellar hemisphere. First cerebrospinal fluid examination revealed no malignant cells, the second one was suspicious for malignant cells. Because of the radiological and clinical evaluation of the patient compatible with the Leptomeningeal Carcinomatosis, intrathecal chemotherapy was performed and his neurological symptoms were improved.

Yeni Taný Mide Karsinomlu Hastada Ýzole Leptomeningeal Karsinomatozis

43 yaþýnda bir erkek karýn aðrýsý ve hematemez ile kabul edildi. Hasta Endoskopik biopsi ile Mide karsinomu tanýsý aldý ve Total Gastrektomi yapýldý.Gastrektomi'nin 6.gününde, baþ aðrýsý ve çift görme yakýnmasý oldu.Beyin MRI bilateral serebellar hemisferde kontrast artýþý ve Leptomeningeal kalýnlaþma gözlendi.Birinci Serebrospinal sývý muayenesinde maliðn hücre gözlenmedi,Ýkinci inceleme maliðn hücre þüphesi içermekteydi.Hastanýn Leptomeningeal Karsinomatosis ile uyumlu klinik ve Radyolojik deðerlendirmelerinden dolayý, Ýntratekal Kemoterpi uygulandý ve Hastanýn nörolojik semptomlarý düzeldi.