Testiküler Feminizasyon Sendromunda Geliþen Seminoma: Hastanýn 7 Yýllýk Takibi

This is a case of a young woman who had testicular feminization and deveioped a seminoma in an undescended testis. This patient admitted to the gynecology service with the complaint of primary amenorrhea. Cytogenetic analysis of chromoso-mes from blood demonstrated a 46, XY karyotype. At iaparoscopy a strict structure beieived to be uterus was noted. The right gonad was found 10x15 mm in size, solid, fusiform, on the pelvic sidewall. There was no left gonad. The procedure was ter-minated following right gonodectomy. Pathology had reported the result as seminoma deveioped in the atrophic testis. She trea-ted with irradiation lor a total dose of 26 Gy in 2 Gy daily fractions by using 6 Ý/ÝV photons of linear accelerator. No recurrence has been found during the postoperative foiiow-up period of 7 years.

Seminoma in A Case of Testicular Feminization Syndrome: Patient Outcome After 7 Years of Follow-up

Bu çalýþmada, testiküler feminizasyon tanýsý konan ve inmemiþ testiste seminom geliþmiþ 23 yaþýnda bir hasta bildirilmiþtir. Kandan alýnan kromozomlarýn sitogenetik analizinde 46 XY karyotipi bulundu. Laparoskopide uterus olduðu düþünülen sert bir yapý bulundu. Sað gonad pelvik duvar içerisinde 10 X 15 mm ebadýnda, fusiform, solid kitle olarak bulundu. Sol gonad yoktu. Sað gonadektomi uygulandý. Patoloji atrofik testisten geliþen seminoma sonucu olarak rapor edildi. Hasta 6 MV foton LINAC kullanýlarak günde 2 Gy fraksiyon ile toplam 26 Gy ýþýnlandý. Bu seminoma olgusu operasyon sonrasý 7 yýl nüksetmemiþ olarak takip edildi.